Positional Mutation View
Viewing mutations by their position AND by sample allows you to quickly see trends between specific mutation and other data, such as expression.
In our Visual spreadsheet each row is a sample. A mutation column shows the transcript along the top with alternating light and dark gray exons in the order of transcription. We buffer our exons to include splice sites. We also include 20kb upstream of the transcription start site to show promoter mutations. Mutations are colored by their functional impact with mutations predicted to not make a protein in red, mutations predicted to make a protein but perhaps with altered function in blue, and synonymous mutations in green. Learn more information about how we characterize mutations.
Get started by going to our Visualization tab, following the wizard to enter your gene of interest into the Visual spreadsheet, which is our default view. Be sure to chose a 'Somatic Mutation SNPs and small INDELs' datasets.